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The alpha-2-delta ligands (gabapentin and pregabalin) have been shown to be as effective as dopamine agonists, but with significantly reduced rates of augmentation, and, unless contraindicated, are now considered first-line therapeutic agents for chronic persistent RLS

BPC-157 is a 15-amino acid gastric peptide fragment that modulates nitric oxide and growth factor pathways

Researchers think this could be because lemon balm may increase beneficial proteins in the brain and help manage problems in the hippocampus (the part of the brain involved in memory and learning) caused by diabetes

PlexusDx recommends baseline lipid testing before starting semaglutide, with follow-up labs at 6 weeks and 3 months to track progress